Dallas researchers have pinpointed a human protein, SIGLEC12, that acts as the trigger for explosive cell death—a process linked to diseases like sepsis, Crohn’s, Alzheimer’s, and some cancers. By tracking how this protein gets activated (thanks to another enzyme, TMPRSS4), scientists now have a clear target for future drugs that could block harmful inflammation. What’s wild is that certain gene variants might help cancer cells dodge this cell death, possibly explaining treatment resistance. Imagine what this could mean for new therapies! Would you want to see these treatments fast-tracked? #Science #DallasScience #MedicalBreakthrough